Airplane travel

The Federal Aviation Administration, or FAA, has ruled that all passengers who require oxygen should be allowed to bring FAA-approved portable oxygen concentrators on all U.S. aircraft with more than 19 seats. Foreign airlines must allow POC on all flights to and from U.S soil. Most portable oxygen concentrators are now approved by the FAA, like the Inogen One, Inogen One G2, Respironics EverGo, SeQual Eclipse, DeVilbiss Igo and a few others.
Train travel
Amtrak also allows medically necessary oxygen equipment onboard. You just need to give them 12 hours' advance notice and assure them you have the needed equipment, including adequate battery back-up. Click for more -800-USA-RAIL.
We recommend you reserve a Superliner Accessible Bedroom for the Amtrak trip. They are lower-level rooms with space for a wheelchair and two adults. Even though oxygen therapy don't use a wheelchair, you'll appreciate having the extra space for the oxygen equipment.
Car travel
Who doesn't love an old-fashioned road trip? Most of today's portable concentrators have a DC power supply that plugs into your car's cigarette lighter outlet. This allows you to power and recharge your concentrator no matter how long your drive.